The majority of people in this productivity-driven culture who value their well-being consider the state of being “awake” as actual complete recovery from their previous state of rest. People experience wakefulness as a deceptive state because it comes from stress hormones which include cortisol and adrenaline that produce their awake state while they actually need to rest. The condition which people describe as being “tired but wired” happens when their sympathetic nervous system continues to function in “fight or flight” mode while their body requires sleep to operate during intense work situations. Your mental state shows you are ready for your next task yet your body needs to rest because it requires recovery. People who choose to ignore their body signals will develop chronic burnout symptoms and sustain physical injuries and suffer from immune system disorders. People who understand their mental state of alertness does not match their physical exhaustion will establish their first defense against complete system failure which protects their health.
Your resting heart rate (RHR)

Provides the most accurate assessment of recovery progress because it serves as a primary indicator of your body’s functioning status. Your body needs extra effort to achieve homeostasis because your parasympathetic nervous system remains inactive while your resting heart rate (RHR) measures up to 10 beats above your normal sleep baseline.
The “Second Wind” at Bedtime

If you feel exhausted all day but suddenly experience a surge of energy right when you try to sleep, this is a classic sign of cortisol dysregulation. The body releases stress hormones to maintain your energy levels during chronic fatigue when the body should take breaks from work.
Increased Irritability and Low Patience

Emotional regulation requires significant cognitive energy. The prefrontal cortex which controls impulse control becomes weak during brain fatigue, resulting in people becoming easily annoyed by minor things and experiencing extreme frustration over small problems that normally would not bother them.
Frequent Illness or Lingering Colds

Sleep and rest are when the immune system produces cytokines which are proteins that target infection and inflammation. Your immune system experiences suppression because you have not gotten enough deep rest, which explains why you are getting sick from every cold that circulates and taking weeks to recover from a minor sniffle.
People who need multiple cups of coffee or energy drinks

To function during the day has created a dependency because they believe their body needs these drinks to achieve alertness. Stimulants create sleep signal suppression which leads to a body debt that results in a more severe crash experience later on.
Restless or Fragmented Sleep

Paradoxically, overtiredness often leads to poor sleep quality. The body prevents access to deep sleep stages (REM and Deep Sleep) because of stress hormones that invade the body during exhaustion, which keeps people awake at night and causes them to toss and turn between sleep cycles.
The body will exhibit neuromuscular fatigue

When there exists a connection failure between brain signals and physical movement. Your motor abilities and reaction times have become impaired because you keep dropping keys and tripping over flat surfaces and bumping into doorframes, even though you do not feel “sleepy.”